Alphabirth adds new transformations to The Binding of Isaac: Rebirth. Each transformation grants unique abilities to Isaac, and are obtained by collecting a set amount of specific items that are both from the base game and from Alphabirth.
| Name | Costume | Pack | Effect |
|---|---|---|---|
| Cyborg |  |
 |
Each additional active charge gives Isaac an all-stats up increase Batteries have an increased chance of spawning on room clear |
| Damned |  |
|
Grants flying Replaces Isaac's health with Black Hearts Upon death, the "Forget Me Now" effect triggers, respawning Isaac at the start of the floor with 3 Black Hearts |
| Waxed |  |
 |
Isaac takes no damage from fire Upon being damaged Isaac shoots out fires in all directions |