Alphabirth adds 3 types of new monsters to The Binding of Isaac. Alphabirth Enemies add completely new enemies to the base game, with unique AI behavior and mechanics. Enemy Variants add new types of variants that can replace existing enemies in the base game, these enemies usually act very similarly to base game enemies with slight modifications. Champions add new champion types to the base game.
Alphabirth Enemies
Enemy Variants
| Name | Image | Pack | Attack Pattern |
|---|---|---|---|
| 3 Eyed Nightcrawler |  |
 |
Burrows up and down periodically, shooting 3 quick shots in succession at Isaac. |
| Bomb Dip |  |
 |
Randomly slides around the room, exploding upon death. |
| Demon Bony |  |
|
Randomly walks around the room, shooting an explosive arcing bone projectile at Isaac when he gets near. |
| Devourer Globin |  |
|
Chases enemies doing contact damage, killing one grants the Devourer Globin a stat boost and switches his target to Isaac. |
| Dip Ulcer |  |
|
Burrows up and down periodically, shooting Dip enemies towards Isaac. |
| Injured Round Worm |  |
|
Burrows up and down periodically, shooting out creep. |
| Kamikaze Fly |  |
|
Bounces around the room dropping bombs. Explodes upon death. |
| Leech Creep |  |
|
Crawls along the wall, shooting out Dart Flies towards Isaac. |
| Lobotomy Gaper |  |
|
Aimlessly wanders around the room, upon death spawns a Brain enemy. |
| Oozing Knight |  |
|
Walks around leaving slowing creep behind. Charges Isaac when he sees him. |
| Round Worm Trio |  |
|
Burrows up and down periodically, shooting a triple shot at Isaac. |
| Zygote |  |
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Randomly hops around the room, splitting into two Zygotes every few seconds. |